Oxycodone tablet a Potent Painkiller

Oxycodone is a generic medicine which contains Oxycodone Hydrochloride as active constituent. Roxicodone belongs to a group of medicines, called opioids analgesics. This medicine helps to reduce moderate to severe pain. Oxycodone shows its action in the brain to change the way your body feels and reacts to pain. This prescription drug is used to manage pain in adults that requires opioid medications.  Oxycodone IR oral tablets are used when non-opioid pain treatments have failed or are not tolerated. If you are having severe pain, you can discuss with your doctor to use an Roxicodone tablet. You can easily Buy Oxycodone Online at a cheap price.

Oxycodone Brands:

Oxycodone tablet is a generic medicine which is used for the treatment of moderate to severe pain. It contains Oxycodone Hydrochloride as an active pharmaceutical ingredient. Its generic name is Oxycodone while difference Oxycodone brands are available:

• Dazidox
• Eth-Oxydose
• Oxaydo
• OxyCONTIN
• OxyCONTIN CR
• Oxydose
• Oxyfast
• Oxy IR
• Roxicodone
• Roxicodone Intensol

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Mechanism of action of Oxycodone:

Oxycodone has a similar mechanism of action as that of other opioids. Oxycodone acts on the central nervous system (CNS) to relieve pain due to its analgesic property. It binds to a receptor, inhibition of adenylyl-cyclase occurs and hyperpolarization of neurons, and decreased excitability.

Oxycodone Dosage

The dosage of this medicine varies for different patients. Follow your doctor’s or label’s instructions. The information below contains only the typical dosage of this medication. If your condition changes, don’t change it unless your doctor tells you to.

Oral dosage form (extended-release capsules):

Oxycodone dosage for severe pain:

      Patients who are not taking narcotics or are opioid resistant: 

• Adults: initial dose, 9 milligrams (mg) every 12 hours with food.

Maximum dose: not more than 288 mg per day.

       Patients transitioning from other narcotics: 

• Adults: The total number of milligrams (mg) per day will be determined by your doctor and will depend on the medication you are using. 

Oral dosage form (capsules):

Oxycodone Dosage for moderate to severe pain:

Patients who are not taking narcotic medicines:

• Adults: initial dose, 5 to 15 milligrams (mg) every 4 to 6 hours as required. Patients change from other narcotic medicines:
• Adults: The total number of milligrams (mg) per day will be determined by your doctor and will depend on the medication you are using. 

Oral dosage form (extended-release tablets):

Oxycodone Dosage for moderate to severe pain:

Patients  shifting from regular oxycodone forms:

• Adults: Every 12 hours one tablet is taken. The total amount of milligrams (mg) per day is similar to the total amount of regular oxycodone that is taken each day. The total amount each day will be given as 2 divided doses during the day. 

         Patients changing from other narcotic medicines:

• Adults: One tablet is taken every 12 hours. The total amount of milligrams (mg) each day will be determined by the doctor according to the narcotic you were using. The total amount each day will be given into 2 divided doses during the day.        Patients not taking narcotics:
• Adults: initial dose, 10 milligrams (mg) every 12 hours. 

Doctor may adjust your dose as needed.

Older adults: initial dose, 3 to 5 milligrams (mg) every 12 hours. 

Oral dosage form (immediate-release tablets):

Oxycodone Dosage For moderate to severe pain:

Patients who are not taking narcotic medicines:

• Adults:Initial dose, 5 to 15 milligrams (mg) every 4 to 6 hours as required. 

       Patients changing from other narcotic medicines:

• Adults: The total amount of milligrams (mg) each day will be determined by the doctor and according to the narcotic you were using. 

Oral dosage forms (liquid concentrate or solution):

Oxycodone Dosage for moderate to severe pain:

• Adults: 10 to 30 milligrams (mg) every 4 hours as required.

Oral dosage forms (solution):

Oxycodone Dosage for moderate to severe pain:

• Adults: 5 to15 milligrams (mg) every 4 hours as per requirement. 

Oral dosage form (tablets):

Oxycodone Dosage for moderate to severe pain:

• Adults: Initial dose, 5 to 15 milligrams (mg) every 4 to 6 hours as needed. 
• For Children the use and dose must be determined by your doctor.
• Doctors may adjust the dose if necessary according to your needs and tolerance.

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Interactions with Oxycodone:

There are many drugs which have interactions with Oxycodone. These drugs can affect the efficacy of Oxycodone which can result in many unwanted side effects. To avoid these harmful effects, you should tell your doctor clearly about all the medications which you are taking previously. Some drugs which have interactions with Roxicodone are as follows:

• Abametapir 
• Abatacept
• Abiraterone
• Acebutolol
• Acetazolamide
• Adalimumab
• Alprazolam 
• Amoxapine
• Betaxolol
• Bisacodyl
• Bupropion
• Bupivacaine
• Carbamazepine 

This list of drug interactions with Oxycodone is not complete as there are many drugs which can interact with it.

Oxycodone Side Effects:

Here is a short list of some minor side effects of Oxycodone Tablets. For other problems, talk to your doctor or pharmacist. Mild side effects of Oxycodone that has been reported are:

• nausea
• vomiting
• constipation
• headache
• dry mouth
• itchiness
• sleepiness

Serious side effects of oxycodone  that has been reported include:

• very low blood pressure, which can result in dizziness and even fainting
• seizures
• adrenal glands problems
• heart problems ie.  increased heart rate and palpitations
• drug dependence 
• withdrawal symptoms

Boxed warning of Oxycodone:

• Misuse and Addiction
• Respiratory depression 
• overdose from accidental ingestion
• If taken with certain drugs, can cause serious risks 
• Neonatal Opioid Withdrawal Syndrome (NOWS)

Precautions and Warnings of Oxycodone:

You do not use Oxycodone if you are using or have used an MAO inhibitor (MAOI) (eg, isocarboxazid [Marplan®], linezolid [Zyvox®], phenelzine [Nardil®], selegiline [Eldepryl®], tranylcypromine [Parnate®]) within the past 14 days.

Oxycodone may cause a serious allergic reaction called anaphylaxis, and it can be life-threatening and requires immediate medical attention. Call your doctor right away if you experience any allergic symptom.

If you think you have taken an overdose of Oxycodone, get emergency help at once. To treat an overdose, doctor may also give naloxone.

Oxycodone may cause sleep-related breathing problems (such as, sleep apnea, sleep-related hypoxemia). If you have sleep apnea, doctor may decrease your dose, while using this medicine.

This medicine (Oxycodone) may be habit-forming. If you feel that the medicine is not working properly do not use more than your prescribed dose. For instructions, call your doctor.

Using this medication during pregnancy can cause serious unwanted side effects, including infant withdrawal syndrome for your newborn. Tell your doctor right away if you think you may be pregnant or if you plan to become pregnant while taking this medicine.

Excessive use of this medicine can lead to infertility (the inability to have children).  If you plan to have children, consult your doctor before using this medicine.

Pros and Cons:

Pros:

• When other medications have failed, Oxycodone works well to treat long term pain.
• Oxycodone is available in different Dosage strengths.
• Lower-cost generic of Oxycodone is also available.
• For longer pain relief, it is available as extended release tablet as well as capsules.

Cons:

• When combined with alcohol or benzodiazepines, it can cause serious breathing problems which can be life-threatening.
• It can become habit-forming which can result in misuse, overdose or addiction.
• Oxycodone can cause unwanted side effects like nausea, vomiting, dizziness etc.